Once saturated with water, the silica gel can be regenerated by heating it to 120 °C (250 °F) for 1-2 hours. However, this regeneration method is long and can be basically uneconomical. The easiest way to regenerate the silica gel is the microwave oven.

Through the use of the microwave oven the regeneration process of silica gel or activated clay (bentonite) is greatly reduced, but it should be noted that only woven-non woven bags can be regenerated. All sachets in DuPont Tyvek package cannot be regenerated: the Tyvek does not allow the dissipation of water vapor that forms inside the bag, the same can inflate and burst like a balloon